HYBRID EVENT: You can participate in person at Zurich, Switzerland. or Virtually from your home or work.

Gabriela Fuyumi Cavallari Inoue

 

Gabriela Fuyumi Cavallari Inoue

Santa Casa de Sao Paulo School of Medical Sciences,
Brazil

Abstract Title: Comparison between systemic immunoinflammatory index (SII) values in patients with psoriasis and psoriatic arthritis

Biography:

Gabriela is a 24-year-old medical student at the Santa Casa de São Paulo School of Medical Sciences.

Research Interest:

The systemic immunoinflammatory index (SII) is an inflammatory marker that contributes to the stratification and prognosis of patients with psoriasis (Ps) and psoriatic arthritis (PsA). The study evaluated the SII in these two populations and compared the values with the presence of cardiovascular risk factors. Information was obtained from laboratory tests of patients diagnosed with Ps and PsA between June 2023 and January 2024. Complete blood count data were used to calculate the SII, with the formula neutrophils×platelets/lymphocytes. Data were analyzed by t-test and χ² and presented as mean±standard deviation or frequency (total number). The significance level adopted was <5%. The JAMOVI-Stats platform was used. A total of 178 patients were included; of these, 53.9% women and 53.9% had Ps. The mean age was 53.9±13.7 years. The mean BMI was 30.4 ± 6.14 kg/m². Regarding Comorbidities:40.8% systemic arterial hypertension, 19.3% dyslipidemia (DLP), 23.6% diabetes, 17.5% hypothyroidism, and 15.3% smokers. In addition, 2.8% acute myocardial infarction and 1.1% stroke. Of those with DLP, 7.4% had Ps and 11.9% had PsA, p < 0.05. To compare the SII value in immunological treatment, 36 patients were analyzed, 66.7% with Ps. The mean age was 53.2±12 years, 54.1±12.4 with PsA and 52.8±12.1 Ps, p<0.05. Before the use of these medications, the SII in the Ps group was 616x10³ mm³ and with PsA 842x10³ mm³, p=ns. After this therapy, 512x10³ mm³ and 784x10³ mm³, in Ps and PsA, respectively, p<0.05. The study showed that before treatment those with PsA had a higher SII value, compared to those with Ps, evidencing greater inflammation and severity. In addition, those with PsA had higher DLP rates.