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Md. Kalimuddin

 

Md. Kalimuddin

National Heart Foundation Hospital & Research Institute,
Bangladesh

Abstract Title: Gender differences in stemi patients undergoing primary pci in bangladesh: Insights from the nami registry

Biography:

Dr. Md. Kalimuddin is a cardiologist specializing in clinical and interventional cardiology, with expertise in pci for both simple and complex cases. He earned his doctor of medicine degree with honors from vitebsk medical institute, ussr, in 1995, followed by an md in cardiology from the national heart foundation hospital & research institute in 2011. Currently serving as an associate professor at the same institute, he has over two decades of experience. He has been actively involved as a co-investigator in several international research studies, including e-ultimaster, ifocus, ioptico study,master dapt, transform ii, ok study, ability diabetes global, ivi-diabetes trial.

Research Interest:

Aims: Worldwide gender disparity in clinical outcome in patients with ST-segment elevation myocardial infarction (STEMI) exists. This study compared clinical outcome between male & female STEMI patients undergoing primary percutaneous coronary intervention (PCI) in Bangladesh over a decade.

Methods and Results: NAMI- registry was conducted in a tertiary cardiac care hospital of Bangladesh over a decade from January 2015 to December 2024. All STEMI patients who underwent primary PCI in our hospital were included in this study. During this period 1854 STEMI patients underwent primary PCI and 1630 (87.9%) patients were male and 224 (12.1%) patients were female. Female were older than male (mean age- 56.89 ± 11.2 years vs 54.1 ± 11.3 years; p=0.001). Female were predominantly hypertensive (74.1% vs 59.8%; p<0.001), diabetic (67.4% vs 54.8%; p<0.001), and had CKD (53.6% vs 36.6%; p<0.001). The mean duration of chest pain (6.38 ± 4.7 hours vs 5.46 ± 4.3 hours; p=0.003) and mean door-to-balloon time (86.88 ± 39.7 vs 81.03 ± 35.6; p=0.02) were prolonged in female than male. Female were more prone to develop hematoma (6.2% vs 3.4%; p=0.03) and required blood transfusion (5.8% vs 2.1%; p=0.001). Female had higher in-hospital death (8.5% vs 4.2%; p=0.004).

Conclusions: Female were older, predominantly hypertensive, diabetic, and had more CKD than male. Female had higher in-hospital mortality than male.